Thermo Fisher Scientific Cytokeratin 10 (Suprabasal Epithelial Marker) Monoclonal Antibody (SPM261)
Cytokeratin 10 단백질을 인식하는 SPM261 단클론 항체로, 인간 및 생쥐 조직에서 상피세포 표지자로 활용 가능. 파라핀 및 PFA 고정 조직의 면역조직화학(IHC)에 적합. 단백질 A/G 정제, 보존제 없음, -20°C 보관.
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Thermo Fisher Scientific Cytokeratin 10 (Suprabasal Epithelial Marker) Monoclonal Antibody (SPM261)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM261 |
| Immunogen | Skin extract of a human Psoriasis patient |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, found in both keratinizing tissues (such as skin) and non-keratinizing cells (such as mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been detected in some microvascular endothelial cells.
At least 20 different cytokeratins (CK), with molecular weights ranging from 40–70 kDa and isoelectric points of 5–8.5, can be identified using two-dimensional gel electrophoresis.
Biochemically, CK proteins are divided into two classes: type I (acidic polypeptides) and type II (basic polypeptides). Each epithelial cell expresses at least one member from each class.
Monoclonal antibodies to cytokeratin proteins serve as useful markers for tumor identification and classification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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