Thermo Fisher Scientific CD62L (L-Selectin) Monoclonal Antibody (DREG-56 (DREG56)), FITC, eBioscience
인간 CD62L(L-Selectin)을 인식하는 DREG-56 단클론 항체로, FITC 형광표지되어 있습니다. 유세포분석(Flow Cytometry)에 최적화되어 있으며, 5 µL(1 µg)/test로 사용됩니다. 염증 부위 림프구 이동 및 HEV 결합 연구에 적합합니다.
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD62L (L-Selectin) Monoclonal Antibody (DREG-56 (DREG56)), FITC, eBioscience
Thermo Fisher Scientific CD62L (L-Selectin) Monoclonal Antibody (DREG-56 (DREG56)), FITC, eBioscience
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL (1 µg)/test
Publications: View 13 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), FITC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | DREG-56 (DREG56) |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10669578 |
Available Formats
- Unconjugated
- Alexa Fluor 532
- APC
- APC-eFluor 780
- Brilliant UV 496 / 615 / 737 / 805
- Brilliant Violet 421 / 480 / 650 / 711 / 786
- eFluor 450
- Functional Grade
- NovaFluor Blue (510, 555, 585, 610-30S, 660-40S, 690, 760)
- NovaFluor Red (710, 725, 755)
- NovaFluor Yellow (570, 590, 660)
- PE / PE-Cyanine5 / PE-Cyanine7 / PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 436 / 600
- Request custom conjugation available
Product Specific Information
Description:
The DREG-56 monoclonal antibody reacts with human CD62L, a 76 kDa member of the selectin family. CD62L is expressed by neutrophils, monocytes, and subsets of T, B, and NK cells. It binds glycosylated, fucosylated, sulfated, and sialylated glycoproteins including CD34, glycam-1, and MAdCAM-1. These interactions mediate lymphocyte rolling on activated endothelium at inflammation sites and homing to high endothelial venules (HEV) of peripheral lymphoid tissues.
Applications Reported:
- Flow cytometric analysis
Applications Tested:
- Pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
- Recommended use: 5 µL (1 µg) per test (final volume 100 µL)
- Applicable for 10⁵–10⁸ cells/test
Excitation: 488 nm
Emission: 520 nm
Laser: Blue Laser
Filtration: 0.2 µm post-manufacturing filtered
Target Information
The human CD62L is a 74–95 kDa glycoprotein member of the selectin family of adhesion receptors. L-Selectin contains:
- Aminoterminal C-type lectin binding domain
- Epidermal growth factor-like domain
- Two short consensus repeat (SCR) sequences
- Spacer region, transmembrane region, and short cytoplasmic region
Human CD62L (L-Selectin) is constitutively expressed on leukocytes including lymphocytes (excluding most memory T cells), monocytes, and polymorphonuclear cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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