Thermo Fisher Scientific CD64 Monoclonal Antibody (10.1), FITC, eBioscience

Applications

Immunohistochemistry (IHC)

• Tested Dilution: Not specified
• Publications: View 1 publication

Flow Cytometry (Flow)

• Tested Dilution: 5 µL (1 µg)/test
• Publications: View 8 publications

Product Specifications

Additional Formats

• Unconjugated
• APC
• APC-eFluor 780
• eFluor 450
• Functional Grade
• NovaFluor Blue 660-120S
• PE
• PE-Cyanine7
• PE-eFluor 610
• PerCP-eFluor 710
• Super Bright 436
• Super Bright 600
• Request custom conjugation

Product Specific Information

The 10.1 monoclonal antibody reacts with human CD64 (FcRI), a 75 kDa type I transmembrane protein. CD64 is the high-affinity receptor for IgG and is involved in antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, and regulation of cytokine production. Monocytes and macrophages express CD64, while mature granulocytes and lymphocytes are negative.

Applications Reported: Flow cytometric analysis
Applications Tested: Pre-titrated and validated for flow cytometry of normal human peripheral blood cells. Recommended usage is 5 µL (1 µg) per test (100 µL final volume, 10⁵–10⁸ cells/test).
Excitation: 488 nm
Emission: 520 nm
Laser: Blue Laser
Filtration: 0.2 µm post-manufacturing filtered

Target Information

CD64 (FCGR1A) encodes a high-affinity Fc-gamma receptor involved in immune response regulation. It is one of three related gene family members located on chromosome 1. CD64 dysfunction has been associated with cervical adenitis and tetrasomy 21.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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