Thermo Fisher Scientific NAG-1 Polyclonal Antibody
Thermo Fisher Scientific의 NAG-1 Polyclonal Antibody는 인간 및 생쥐 NAG-1 단백질을 인식하는 Rabbit IgG 항체로, WB, ELISA, IP에 적합합니다. Protein A로 정제된 액상 항체이며, 안정적인 저장 및 재현성 높은 결과를 제공합니다.
- 카탈로그번호
- 210-401-B68x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific NAG-1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Protein-A purified antibody prepared by repeated immunizations with an MBP-tagged recombinant protein produced in E. coli corresponding to full-length mouse NAG-1 protein. Cross reactivity to MBP was removed via cross-adsorption chromatography. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.13 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at -20°C prior to opening.
- Aliquot contents and freeze at -20°C or below for extended storage.
- Avoid cycles of freezing and thawing.
- Centrifuge product if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
This antibody reacts with endogenous NAG-1 protein from mouse and human tissues.
A BLAST analysis suggests reactivity with NAG-1 from mouse and rat (100% and 97% homology, respectively), and with Chinese hamster (92% homology).
Cross-reactivity with NAG-1 from other sources has not been determined.
Target Information
GDF-15 belongs to the TGF-beta cytokine family, which plays an important role in prenatal development, postnatal growth, and tissue remodeling.
It is predominantly expressed in the placenta and to a lesser extent in other tissues.
Elevated levels of GDF-15 in the sera of pregnant women suggest involvement in gestation and embryonic development.
GDF-15 generally exerts tumor suppressive activities and is produced in response to p53 pathway activation.
Serum GDF-15 levels correlate with neoplastic progression in certain colorectal, pancreatic, and prostate cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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