Thermo Fisher Scientific Avian Influenza H5N1 HA Monoclonal Antibody (14B1E2G6)

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

ELISA

• Tested Dilution: 1:1,000–1:2,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for H5N1 (A/Anhui/1/2005) HA.

Target Information

Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and the United States. The virus spread globally, leading to a pandemic declared by the WHO on June 11, 2009.

Influenza A virus has one of sixteen possible Hemagglutinin (HA) surface proteins and one of nine possible Neuraminidase (NA) surface proteins. Hemagglutinin facilitates viral attachment, while Neuraminidase is involved in viral release. These proteins elicit immune responses that can prevent infection or reduce viral replication.

The 2009 swine-origin H1N1 strain combined genetic material from human, swine, and avian influenza viruses, with additional H3N2 pig genes of Eurasian origin. The antigenic differences between this new strain and seasonal H1N1 suggest limited pre-existing immunity in humans, though older populations may have partial protection.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.