Thermo Fisher Scientific Avian Influenza H5N1 HA Monoclonal Antibody (11)

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

ELISA

• Tested Dilution: 1:1,000–1:2,000

Product Specifications

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

This antibody has specificity for:

• H5N1 (A/Anhui/1/2005) HA
• H5N1 (A/bar-headed goose/Qinghai/14/2008) HA

Target Information

Influenza A virus is a major public health threat, responsible for over 30,000 deaths annually in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus emerged in Mexico and the United States, spreading globally and leading to a pandemic declaration by the WHO on June 11, 2009.

Influenza A virus possesses sixteen possible Hemagglutinin (HA) surface proteins and nine possible Neuraminidase (NA) surface proteins:

• HA facilitates viral attachment.
• NA enables viral release.

These proteins elicit immune responses that can prevent infection or reduce viral replication. The 2009 H1N1 strain contained a unique genetic combination of human, swine, and avian influenza genes, with additional H3N2 genes from Eurasian pigs of recent human origin. Due to its distinct antigenic properties, human immunity against this strain was limited, though older age groups showed partial protection.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.