Thermo Fisher Scientific AP2 alpha Monoclonal Antibody (R.387.0)
AP2 alpha 단백질을 인식하는 Rabbit monoclonal 항체. Western blot 및 Immunocytochemistry에 최적화되어 있으며 Human, Mouse, Rat 등에서 반응. 고순도의 affinity chromatography 정제 제품으로 -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100 | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | R.387.0 |
| Immunogen | Synthetic peptide corresponding to human AP-2α |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 94.8 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10982796 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in important biological functions such as eye, face, body wall, limb, and neural tube development. They also suppress genes including MCAM/MUC18, C/EBP alpha, and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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