Thermo Fisher Scientific Naja kaouthia Cobra Venom Factor Polyclonal Antibody
Thermo Fisher Scientific의 Naja kaouthia Cobra Venom Factor Polyclonal Antibody는 뱀 독성 인자 단백질을 타겟으로 하는 토끼 유래 IgG 항체입니다. Western blot 및 direct ELISA에 적합하며, Protein G로 정제된 고농도 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:5,000
- Direct ELISA: Tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Reptile |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Naja kaouthia Cobra venom factor protein (733–984aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2902334 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb acts as a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which cannot form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to complement regulatory factors H (CFH) and I (CFI), leading to continuous complement activation and depletion of complement activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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