Thermo Fisher Scientific Pannexin 1 Polyclonal Antibody
Pannexin-1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF 등 다양한 응용에 사용 가능. Protein G 정제 및 PBS/glycerol buffer로 보관. 인간 시료에 반응하며, 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:200 |
| Immunocytochemistry (ICC/IF) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Pannexin-1 protein (288–426 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.585 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2902335 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
The pannexin gene family encodes a second class of putative gap junction proteins that are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels.
Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is more distantly related. PANX1 forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. It may function as a Ca²⁺-leak channel to regulate ER Ca²⁺ homeostasis and neural stem/progenitor cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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