Thermo Fisher Scientific CD200R Polyclonal Antibody
CD200R 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC(Paraffin)에서 검증됨. 인간과 생쥐 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol 완충액에 보관되며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Cell surface glycoprotein CD200 receptor 1 protein (226–325 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2902333 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein. Both the receptor and its ligand are cell surface glycoproteins containing two immunoglobulin-like domains. CD200R is expressed mainly on cells of the myeloid lineage, and the receptor-ligand interaction may act as a downregulatory signal for these cells.
In mice, CD200R is primarily expressed by peripheral blood monocytes and neutrophils, as well as other leukocytes such as T-lymphocytes and mast cells. Studies suggest that CD200R may control myeloid function in a tissue-specific manner. Alternative splicing of CD200R results in multiple transcript variants.
Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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