Thermo Fisher Scientific PIGW Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to residues in human PIGW

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2553955

Product Specific Information

This antibody detects endogenous protein at a molecular weight of 57 kDa.

Purity is >95% by SDS-PAGE.

Target Information

Phosphatidylinositol-glycans (PIGs) are multi-pass transmembrane proteins that localize to the endoplasmic reticulum. PIGs exhibit various functions, but all are crucial for the biosynthesis of the glycosylphosphatidylinositol (GPI)-anchor. Some PIG proteins are components of the GPI transamidase complex and play a role in the recognition of either the GPI attachment signal or the lipid portion of GPI. Other PIGs belong to the glycosyltransferase complex and function in the transfer of N-acetylglucosamine (GlcNAc) to phosphatidylinositol (PI). A variety of other PIGs play distinct roles in GPI synthesis including mannosylation of the GPI-anchor. PIG-W (Phosphatidylinositol-glycan biosynthesis class W protein) is a 504 amino acid multi-pass membrane protein that functions in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.