Thermo Fisher Scientific PGC-1beta Polyclonal Antibody
Rabbit polyclonal antibody targeting human PGC-1 beta (PPARGC1B). Suitable for Western blot and immunoprecipitation. Predicted to react with mouse and rat. Supplied as unconjugated liquid form, 1 mg/mL concentration, stored at 4°C.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunoprecipitation (IP)
- Tested Dilution: 10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human peroxisome proliferator-activated receptor gamma coactivator 1 beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
Target Information
PGC-1 beta is a tissue-specific co-activator that enhances the activity of estrogen receptor alpha.
The co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner.
Ectopic expression of this protein has been shown to lead to increased mitochondrial number and basal oxygen consumption.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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