Thermo Fisher Scientific CAP-H2 Polyclonal Antibody
인간 CAP-H2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 4°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunoprecipitation (IP) | 10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 555 and 605 of human chromosome-associated protein H2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes that are involved in chromosome condensation. Proper condensation is essential for accurate segregation of replicated sister chromatids prior to metaphase.
The condensin I complex includes SMC2, SMC4, CAP-H, CAP-G, and CAP-D2. The condensin II complex contains alternate non-SMC subunits CAP-G2, CAP-H2, and CAP-D3. CAP-H2, also known as Non-SMC condensin II complex subunit H2 (NCAPH2) or kleisin beta isoform 2, forms part of a regulatory subcomplex required for activation of SMC ATPases and mitosis-specific chromatin binding. The individual roles of each non-SMC protein in activation remain under investigation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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