Thermo Fisher Scientific NBL1 Polyclonal Antibody
NBL1 단백질을 인식하는 Thermo Fisher Scientific의 goat polyclonal antibody입니다. WB, IHC, Neutralization 등 다양한 응용에 사용 가능하며, 인간 종에 반응합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (IHC) | 5–15 µg/mL |
| Neutralization (Neu) | Assay-Dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human DAN Ala17–Asp180 (Ala36Arg) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608812 |
Product Specific Information
- In direct ELISAs, approximately 25% cross-reactivity with recombinant mouse (rm) DAN is observed.
- Less than 1% cross-reactivity with recombinant chicken Caronte, rmGremlin, and recombinant human Cerberus 1 is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
This gene product is the founding member of the evolutionarily conserved CAN family of proteins, which contain a domain resembling the CTCK motif found in a number of signaling molecules.
These proteins are secreted and act as BMP antagonists by binding to BMPs and preventing them from interacting with their receptors.
They may play an important role during growth and development.
Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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