Thermo Fisher Scientific PDIA3 Monoclonal Antibody (OTI4D7), TrueMAB
Human PDIA3 단백질을 인식하는 mouse monoclonal antibody로, Western blot과 IHC에 적합. TrueMAB 형식의 고순도 항체로, 재조합 단백질(aa 140–505)을 면역원으로 제작. PBS buffer에 동결건조 형태로 제공되며, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D7 |
| Immunogen | Human recombinant protein fragment (aa 140–505 of human PDIA3) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain ~1 mg/mL antibody concentration.
For conjugation experiments, perform additional desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PDIA3 encodes an endoplasmic reticulum protein that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins.
Although previously thought to be a phospholipase, PDIA3 actually exhibits protein disulfide isomerase activity.
Complexes of lectins and PDIA3 promote protein folding by facilitating disulfide bond formation in glycoprotein substrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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