Thermo Fisher Scientific Calpain 1 Monoclonal Antibody (CAPN1/1530)
Calpain 1 단백질을 표적하는 Mouse monoclonal 항체로, IHC(P), IHC(PFA), ELISA에 적합합니다. Recombinant full-length human CAPN1로부터 유래하며, Protein A/G로 정제된 Liquid 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| ELISA | 2–4 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CAPN1/1530 |
| Immunogen | Recombinant full-length human CAPN1 protein (amino acids 1–714) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases that function as nonlysosomal, intracellular cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes are heterodimers composed of distinct large catalytic subunits associated with a common small regulatory subunit.
The CAPN1 gene encodes the large subunit of the ubiquitous enzyme calpain 1. Several transcript variants encoding two different isoforms have been identified.
Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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