Thermo Fisher Scientific Adalimumab Monoclonal Antibody (3C2)
인간 Adalimumab을 인식하는 Mouse IgG1 단일클론 항체로, ELISA 등 연구용에 적합합니다. Lyophilized 형태로 제공되며 Protein A로 정제되었습니다. TNF-α 결합 특성을 연구하는 데 활용됩니다.
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Applications
- ELISA (ELISA)
Tested Dilution
- 0.005–0.1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3C2 |
| Immunogen | Adalimumab |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
Adalimumab, sold under the trade name Humira among others, is a medication used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn’s disease, ulcerative colitis, chronic psoriasis, hidradenitis suppurativa, and juvenile idiopathic arthritis.
Adalimumab is a TNF-inhibiting, anti-inflammatory biologic medication. It binds to tumor necrosis factor-alpha (TNFα), which normally binds to TNFα receptors, leading to the inflammatory response of autoimmune diseases.
By binding to TNFα, adalimumab reduces this inflammatory response. Because TNFα is also part of the immune system, treatment with adalimumab may increase the risk of infections.
Target Information
Adalimumab (Humira) is a humanized monoclonal antibody approved by the U.S. FDA for treatment of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn’s disease, ulcerative colitis, chronic psoriasis, hidradenitis suppurativa, and juvenile idiopathic arthritis.
Adalimumab binds to TNFα and blocks its interaction with TNFα receptors, reducing the inflammatory response of autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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