Thermo Fisher Scientific Adalimumab Monoclonal Antibody (15C7)
Adalimumab을 인식하는 마우스 단클론 항체로, ELISA 등 연구용으로 사용됩니다. TNF-α 결합 억제를 통해 자가면역 질환 연구에 활용됩니다. 동결건조 형태로 제공되며, 재구성 후 0.5 mg/mL 농도로 사용 가능합니다. For Research Use Only.
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Applications
- ELISA (ELISA)
Tested Dilution: 0.001–0.1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 15C7 |
| Immunogen | Adalimumab |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Lyophilized antibody should be reconstituted with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
Adalimumab, commercially known as Humira, is a TNF-inhibiting monoclonal antibody used to treat autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, chronic psoriasis, hidradenitis suppurativa, and juvenile idiopathic arthritis.
It binds to tumor necrosis factor-alpha (TNFα), preventing its interaction with TNFα receptors and thereby reducing inflammatory responses. Because TNFα is also involved in immune defense, treatment with adalimumab may increase susceptibility to infections.
Target Information
Adalimumab (Humira) is a humanized monoclonal antibody approved by the U.S. FDA for the treatment of multiple autoimmune diseases. It specifically binds TNFα and blocks its receptor interaction, reducing inflammation associated with these conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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