Thermo Fisher Scientific ITFG2 Monoclonal Antibody (OTI3A6), TrueMAB
ITFG2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 Immunocytochemistry에 적합. HEK293T 세포에서 생산된 full-length human recombinant ITFG2를 면역원으로 사용. Lyophilized 형태, PBS buffer 포함, 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ITFG2 Monoclonal Antibody (OTI3A6), TrueMAB
Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A6 |
| Immunogen | Full length human recombinant protein of human ITFG2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ITFG2 is part of the KICSTOR complex functioning in the amino acid-sensing branch of the TORC1 signaling pathway. It recruits the GATOR1 complex to lysosomal membranes, enabling its interaction with GATOR2 and RAG GTPases. ITFG2 functions upstream of RAG GTPases and is required to negatively regulate mTORC1 signaling in the absence of amino acids. Without the KICSTOR complex, mTORC1 remains constitutively localized to lysosomes and activated. The complex may also regulate mTORC1 in response to glucose.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.