Thermo Fisher Scientific H3K79me1me2me3 Recombinant Rabbit Monoclonal Antibody (SR42-06)
Recombinant rabbit monoclonal antibody targeting H3K79me1/me2/me3 for WB and IHC applications. High specificity and lot-to-lot consistency. Suitable for human, mouse, and rat samples. Provided in liquid form, 1 mg/mL concentration, stored at 4°C or -20°C.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SR42-06 |
| Immunogen | Synthetic peptide within Human Histone H3 aa 56–105 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809304 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened for optimal production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
Histone H3 is a DNA-binding protein forming part of the chromatin structure in eukaryotic cells. Together with core histones, it contributes to nucleosome formation and plays key roles in:
- Transcription regulation
- DNA repair and replication
- Chromosomal stability
The N-terminal tail of histone H3 can undergo post-translational modifications such as methylation, acetylation, and phosphorylation, influencing chromatin structure and gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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