Thermo Fisher Scientific GDNF Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

1:50-1:500

-

ELISA (ELISA)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Chicken / IgY

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide mixture based on the human GDNF protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

IgY fraction

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2111385

Product Specific Information

PA1-9524 detects GDNF in human, mouse and rat samples.

PA1-9524 has been successfully used in Western blot, ELISA, and Immunohistochemistry procedures. By Western blot, PA1-9524 detects a 24 kDa protein representing GDNF.

PA1-9524 immunogen is a synthetic peptide based on the human GDNF protein.

Store product at 4ºC for up to one week, and -20ºC for long term storage.

Target Information

GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson`s disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.