Thermo Fisher Scientific GDNF Polyclonal Antibody
GDNF 단백질을 인식하는 다클론 항체로, Western blot, ELISA, IHC에 적합합니다. Human, Mouse, Rat 시료에서 반응하며 IgY 분획으로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 2 publications |
| Immunohistochemistry (IHC) | 1:50–1:500 | - |
| ELISA | 1:500–1:2,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide mixture based on the human GDNF protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | IgY fraction |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2111385 |
Product Specific Information
PA1-9524 detects GDNF in human, mouse, and rat samples.
It has been successfully used in Western blot, ELISA, and Immunohistochemistry procedures.
By Western blot, PA1-9524 detects a 24 kDa protein representing GDNF.
The immunogen is a synthetic peptide based on the human GDNF protein.
Store at 4°C for up to one week, and -20°C for long-term storage.
Target Information
GDNF (Glial cell line-derived neurotrophic factor) is a glycosylated, disulfide-bonded homodimer molecule.
It was first discovered as a potent survival factor for midbrain dopaminergic neurons and shown to rescue these neurons in animal models of Parkinson’s disease.
GDNF is about 100 times more efficient as a survival factor for spinal motor neurons than neurotrophins.
It enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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