Thermo Fisher Scientific IL-3 Monoclonal Antibody (653A10B1 1G8)

Applications

ELISA

• Assay-dependent
• Recommended as a capture antibody in Sandwich ELISA applications
• View 3 publications

Miscellaneous PubMed

• View 1 publication

Product Specifications

Target Information

Interleukin 3 (IL-3), also known as Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells, and eosinophils.
IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell, and monocytic lineages.
Most of these functions are enhanced or dependent on co-stimulation with other cytokines.
Human and mouse IL-3 share only 29% sequence identity at the amino acid level, and IL-3 activity is highly species-specific — human IL-3 has no activity on mouse cells.
IL-3 supports proliferation of a broad range of hematopoietic cell types and is involved in cell growth, differentiation, and apoptosis.
It has also been shown to possess neurotrophic activity and may be associated with neurologic disorders.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.