Thermo Fisher Scientific IL-3 Monoclonal Antibody (653A10B1 1G8)
인간 IL-3를 인식하는 마우스 단클론 항체로 ELISA(Sandwich)용 캡처 항체로 권장됩니다. 비결합형 액상 형태이며 1 mg/mL 농도로 제공됩니다. Protein A로 정제되었으며 PBS(pH 7.4)에 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
ELISA
- Assay-dependent
- Recommended as a capture antibody in Sandwich ELISA applications
- View 3 publications
Miscellaneous PubMed
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 653A10B1 1G8 |
| Immunogen | Recombinant human IL-3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.5 mg/mL sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536262 |
Target Information
Interleukin 3 (IL-3), also known as Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells, and eosinophils.
IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell, and monocytic lineages.
Most of these functions are enhanced or dependent on co-stimulation with other cytokines.
Human and mouse IL-3 share only 29% sequence identity at the amino acid level, and IL-3 activity is highly species-specific — human IL-3 has no activity on mouse cells.
IL-3 supports proliferation of a broad range of hematopoietic cell types and is involved in cell growth, differentiation, and apoptosis.
It has also been shown to possess neurotrophic activity and may be associated with neurologic disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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