Thermo Fisher Scientific Cyclin L1 Polyclonal Antibody
Cyclin L1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 응용에 적합하며, 고순도 항원 친화 크로마토그래피로 정제됨. Human, Mouse, Rat 반응성, 액상 형태로 -20°C 보관.
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Thermo Fisher Scientific Cyclin L1 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:3,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human Cyclin-L1 (amino acids 483–506, UniProt ID: Q9UK58-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635203 |
Product Specific Information
This antibody detects endogenous levels of total Cyclin L1 protein.
Target Information
FUS/TLS, originally described as fused in sarcoma, is involved in various cellular processes and associated with multiple diseases. FUS binds single- and double-stranded DNA, serving as a site for transcription factor recognition. Dysregulation of FUS functions is implicated in cancers such as liposarcoma, lipoma, and leukemia. Moreover, abnormal RNA-binding of FUS is linked to amyotrophic lateral sclerosis (ALS), causing mislocalization and neuronal pathology. Proper regulation of FUS is essential for maintaining healthy cellular functions.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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