Thermo Fisher Scientific Phospho-DOK2 (Tyr299) Polyclonal Antibody
DOK2 단백질의 Tyr299 인산화 부위를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot에서 1:500~1:2,000 희석 비율로 사용 가능. Human 및 Mouse 시료에 반응하며, PBS/glycerol buffer에 보관. 연구용으로 적합.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DOK2 (Accession O60496), corresponding to amino acid residues around phosphorylated Tyr299. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816175 |
Product Specific Information
This antibody detects endogenous levels of DOK2 only when phosphorylated at Tyrosine 299.
Target Information
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein associated with CML. This encoded protein binds p120 from CML cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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