Thermo Fisher Scientific PODXL Monoclonal Antibody (OTI8D6), TrueMAB
인간 PODXL 단백질을 인식하는 마우스 단클론 항체로, IHC(P) 등 연구용에 적합합니다. 무보존제, 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다. 세포 분화 및 혈관 내피 관련 연구에 활용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8D6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 32–461 of human PODXL produced in HEK293 cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes a member of the sialomucin protein family. The encoded protein is an important component of glomerular podocytes — highly differentiated epithelial cells with interdigitating foot processes covering the glomerular basement membrane.
Other biological activities include:
- Binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to cytoskeletal elements
- Playing a role in hematopoietic cell differentiation
- Expression in vascular endothelium and binding to L-selectin
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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