Thermo Fisher Scientific CD8b Monoclonal Antibody (SIDI8BEE), Brilliant Ultra Violet 661, eBioscience
인간 및 비인간 영장류 CD8β 항원 검출용 단클론 항체로, Brilliant Ultra Violet 661 형광체 결합. Flow cytometry에 최적화되어 있으며, UV 레이저(355 nm) 사용 장비에 적합. 고감도, 낮은 비특이적 결합, 안정적 형광 신호 제공.
- 카탈로그번호
- 376-5273-4x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD8b Monoclonal Antibody (SIDI8BEE), Brilliant Ultra Violet 661, eBioscience
Thermo Fisher Scientific CD8b Monoclonal Antibody (SIDI8BEE), Brilliant Ultra Violet 661, eBioscience
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL (0.125 µg)/test
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Brilliant Ultra Violet™ 661 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SIDI8BEE |
| Conjugate | Brilliant Ultra Violet™ 661 |
| Excitation / Emission Max | 349 / 659 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.2, with BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
- Unconjugated
- Brilliant Violet 605
- eFluor 660
- NovaFluor Blue 510
- NovaFluor Blue 585
- NovaFluor Blue 610-70S
- NovaFluor Blue 690
- NovaFluor Red 725
- NovaFluor Red 755
- NovaFluor Yellow 755
- PE
- PE-Cyanine7
- PerCP-eFluor 710
- Super Bright 436
- Super Bright 702
- Request custom conjugation
Product Specific Information
The SIDI8BEE monoclonal antibody reacts with human and rhesus macaque CD8 beta. The CD8b chain associates with the CD8a chain to form the CD8ab heterodimer expressed on thymocytes and peripheral cytotoxic T cells. CD8 receptor binds to MHC class I, playing a key role in T cell development and activation.
SIDI8BEE detects CD8 beta in both CD8ab heterodimer and CD8bb homodimer.
Applications Reported: Flow cytometric analysis
Applications Tested: Pre-diluted and tested on normal human peripheral blood cells. Recommended use: 5 µL (0.125 µg) per test in 100 µL final volume.
Fluorochrome: Brilliant Ultra Violet™ 661 (BUV661) emits at 660 nm, for UV laser (355 nm) equipped cytometers.
Staining Panel Compatibility: Use Super Bright Complete Staining Buffer (SB-4401-42) or Brilliant Stain Buffer™ (00-4409-75) to minimize non-specific polymer interactions.
Light Sensitivity: Protect from light to prevent photo-induced oxidation.
Fixation: Samples can be stored in IC Fixation Buffer (00-8222-49) or 1-step Fix/Lyse Solution (00-5333-54) for up to 3 days at 4°C in the dark.
Excitation: 350 nm
Emission: 660 nm
Laser: Ultraviolet Laser
BRILLIANT ULTRA VIOLET™ is a trademark of Becton, Dickinson and Company, used under license. Powered by Sirigen.
Target Information
CD8B antigen is a cell surface glycoprotein on cytotoxic T lymphocytes, mediating cell-cell interactions within the immune system. It acts as a coreceptor with T-cell receptor to recognize antigens presented by APCs in the context of MHC class I.
Functional coreceptor forms include alpha homodimers or alpha-beta heterodimers. Both chains share homology with immunoglobulin variable light chains.
This gene encodes CD8 beta chain isoforms, with multiple alternatively spliced variants and a pseudogene located on chromosome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.