Thermo Fisher Scientific D4 Dopamine Receptor Polyclonal Antibody
D4 Dopamine Receptor를 인식하는 Rabbit Polyclonal Antibody로, Western blot과 ELISA에 적합합니다. Mouse 시료에 반응하며, 세포막 다중통과 단백질 검출에 유용합니다. Affinity Chromatography로 정제되었고, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human DRD4 (P21917) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.35 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806308 |
Product Specific Information
- Positive Samples: Mouse liver
- Cellular Location: Cell membrane, Multi-pass membrane protein
Immunogen sequence:
MGNRSTADAD GLLAGRGPAA GASAGASAGL AGQGAAALVG GVLLIGAVLA GNSLVCVSVA TERALQTPTN SFIVSLAAAD LLLALLVLPL FVYSEVQGGA
Target Information
This gene encodes the D4 subtype of the dopamine receptor, a G-protein coupled receptor that inhibits adenylyl cyclase. It is a target for drugs used in the treatment of schizophrenia and Parkinson’s disease. Mutations in this gene are associated with behavioral phenotypes such as autonomic nervous system dysfunction, ADHD, and novelty seeking.
The gene contains a polymorphic number (2–10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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