Thermo Fisher Scientific UHRF1 Polyclonal Antibody
UHRF1 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 고순도 Affinity chromatography 정제 및 PBS/glycerol buffer로 안정적 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human UHRF1 (Accession Q96T88), corresponding to amino acid residues L22–L72 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900739 |
Product Specific Information
Antibody detects endogenous levels of total UHRF1.
Target Information
This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases.
The protein binds to specific DNA sequences and recruits a histone deacetylase to regulate gene expression.
Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle.
It plays a major role in the G1/S transition by regulating topoisomerase IIα and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint.
Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-116105_UHRF1_Q96T88-1_Rabbit.svg, PA5-116105_UHRF1_Q96T88-1_Rabbit_PDP.jpeg)
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