Thermo Fisher Scientific ULK2 Polyclonal Antibody
ULK2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, 인간·마우스·랫에서 반응합니다. Western blot 및 IHC(P) 실험에 적합하며, 액상 형태로 -20°C 보관합니다. 자가포식 관련 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ULK2 (Accession Q8IYT8), corresponding to amino acid residues Q540–F590 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900740 |
Product Specific Information
Antibody detects endogenous levels of total ULK2.
Target Information
ULK2, also known as ATG1B, is a key serine/threonine protein kinase acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. ULK2 is also involved in early neuronal growth and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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