Thermo Fisher Scientific BAFF Monoclonal Antibody (2B)

Applications

Tested Dilution

Publications

ELISA (ELISA)

5-6 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

2B

Immunogen

Recombinant full length mature human CD257 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BAFF (BLyS),uniProtId:Q9Y275-1,ncbiNodeId:9606,antigenRange:1-285,antigenLength:285,antigenImageFileName:MA1-82774_BAFF_BLyS_Q9Y275-1_House_mouse.svg,antigenImageFileNamePDP:MA1-82774_BAFF_BLyS_Q9Y275-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.2

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_927103

Product Specific Information

Reconstitute with 0.5 mL of distilled water. Prior to reconstitution, store at 4ºC. After reconstitution, store undiluted at -20ºC, avoiding freeze/thaw cycles.

Mouse anti Human CD257 antibody, clone 2B recognizes CD257, also known as BAFF/BLyS.

Target Information

BAFF is a membrane bound cytokine expressed by B cell lineage cells. The soluble form of the cytokine binds to the receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. BAFF is a potent B cell activator, and important for the proliferation and differentiation of B cells. BAFF is also expressed by T lymphocytes and has been shown to promote T cell activation and survival. Isoforms representing alternatively spliced, and glycosylated variants have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.