Thermo Fisher Scientific CD137 (TNFRSF9) Monoclonal Antibody (OTI7C3)
인간 CD137(TNFRSF9)을 인식하는 마우스 단클론 항체로 Flow Cytometry에 적합. HEK293T에서 생산된 전장 재조합 단백질을 면역원으로 사용. 비접합형 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- TA813093
- 판매단위
- pk
카탈로그
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:100
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7C3 |
| Immunogen | Full length human recombinant protein of human TNFRSF9 (NP_001552) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells.
CD137 signaling contributes to the survival of activated T cells and CD8+ memory T cells, promotes clonal expansion of T cells, and modulates myelopoiesis and dendritic cell development. Triggered CD137 induces cytokine release that regulates peripheral monocyte survival. Soluble forms of CD137 may act as a negative control mechanism for certain immune responses.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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