Thermo Fisher Scientific CD137 (TNFRSF9) Monoclonal Antibody (OTI6D7)
인간 CD137(TNFRSF9)을 인식하는 단클론 항체로, Western blot과 유세포분석(Flow Cytometry)에 적합합니다. 마우스 IgG1 형식이며 비결합형 액상 제품으로, 고순도 친화 크로마토그래피 정제. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6D7 |
| Immunogen | Full length human recombinant protein of human TNFRSF9 (NP_001552) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol, 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling supports survival and clonal expansion of activated and memory CD8+ T cells, while suppressing myelopoiesis and dendritic cell development. Activation of CD137 induces cytokine release that regulates peripheral monocyte survival. Soluble CD137 may act as a negative regulator in certain immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: TA813072_4-1BB_CD137_Q07011-1_House_mouse.svg, TA813072_4-1BB_CD137_Q07011-1_House_mouse_PDP.jpeg)
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