Thermo Fisher Scientific CD137 (TNFRSF9) Monoclonal Antibody (OTI14C10)
인간 CD137(TNFRSF9)을 인식하는 Mouse IgG1 단클론 항체로, Flow Cytometry에 적합합니다. HEK293T 세포에서 발현된 재조합 단백질을 면역원으로 사용하였으며, 액상 형태로 1 mg/mL 농도입니다. 친화 크로마토그래피로 정제되었으며, -20°C에서 보관합니다.
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Applications
- Flow Cytometry (Flow): Tested dilution 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI14C10 |
| Immunogen | Full length human recombinant protein of human TNFRSF9 (NP_001552) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol, 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling contributes to the survival and expansion of activated and memory T cells, while also regulating myelopoiesis and dendritic cell development. Activation of CD137 induces cytokine release that influences peripheral monocyte survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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