Thermo Fisher Scientific Transthyretin (Prealbumin) Monoclonal Antibody (TTR, 4296)
Human Transthyretin(Prealbumin)을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, Peptide array에 사용 가능. Recombinant full-length TTR 항원으로 제작. 단백질 A/G로 정제된 200 µg/mL 액상 시약. 연구용 한정.
- 카탈로그번호
- 7276-MSM6-P0
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TTR, 4296 |
| Immunogen | Recombinant human full-length Transthyretin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA-fixed): Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Transthyretin (TTR), also known as prealbumin, is a plasma protein that transports thyroxine and retinal-binding protein. It is primarily produced in the liver and secreted into plasma. TTR accounts for approximately 25% of cerebrospinal fluid (CSF) protein, suggesting selective transport across the blood-CSF barrier or synthesis within the CNS. It is found in neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. Over 40 different mutations in the TTR gene have been associated with amyloid deposition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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