
Thermo Fisher Scientific EXD1 Monoclonal Antibody (OTI4G1), TrueMAB
인간 EXD1 단백질을 인식하는 단클론 항체로 Western blot 및 유세포분석에 사용 가능. TrueMAB 형식으로 고순도 친화 크로마토그래피 정제. 동결건조 형태로 제공되며, 보존제 무첨가. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G1 |
| Immunogen | Full length human recombinant protein of human EXD1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
EXD1 is an RNA-binding component of the PET complex, essential for piRNA processing during spermatogenesis.
The piRNA metabolic process represses transposable elements during meiosis through piRNA–Piwi protein complexes, maintaining germline integrity.
The PET complex facilitates secondary piRNA metabolism, enabling PIWIL2 slicing-triggered loading of PIWIL4 piRNAs.
Within this complex, EXD1 likely acts as an RNA adapter and is considered an inactive exonuclease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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