Thermo Fisher Scientific Bcl11a Recombinant Rabbit Monoclonal Antibody (BLR073G)
Bcl11a 단백질을 인식하는 토끼 단클론 항체로, Western blot, Flow cytometry, Immunoprecipitation에 적합합니다. 인간 및 생쥐 시료에서 반응하며, 고순도의 정제 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Flow Cytometry (Flow) | 0.2 µL per 1 x 10⁶ cells |
| Immunoprecipitation (IP) | 20 µL / 1 mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR073G |
| Immunogen | Peptide representing a region between residue 1 and 50 of human B cell CLL/lymphoma 11A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1000 µg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 7.8–8.6 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Target Information
This gene encodes a C2H2-type zinc-finger protein similar to the mouse Bcl11a/Evi9 protein. The mouse gene is a common site of retroviral integration in myeloid leukemia and may function as a leukemia disease gene through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated and may be involved in lymphoma pathogenesis, as translocations associated with B-cell malignancies can deregulate its expression. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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