Thermo Fisher Scientific ARHGEF2 Monoclonal Antibody (OTI5F2), TrueMAB
ARHGEF2 단백질을 인식하는 Mouse Monoclonal Antibody. Western blot 및 Flow cytometry에 사용 가능. Human, Mouse, Rat 반응성. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F2 |
| Immunogen | Full length human recombinant protein of human ARHGEF2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
GEF-H1 activates Rho GTPases by promoting GDP-GTP exchange.
Rho GTPases are involved in various cellular processes such as:
- Epithelial barrier permeability
- Cell motility and polarization
- Dendritic spine morphology
- Antigen presentation
- Leukemic cell differentiation
- Cell cycle regulation
- Innate immune response
- Cancer progression
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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