Thermo Fisher Scientific DDX4 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal DDX4 항체로 Western Blot에 적합. Affinity chromatography로 정제되었으며 PBS/glycerol buffer에 보관. Germ cell 발현 연구 및 RNA helicase 관련 연구에 유용.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around aa.273–277 (T-I-L-V-E) derived from Human DDX4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2635142 |
Product Specific Information
The antibody detects endogenous levels of total DDX4 protein.
Target Information
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases. They are involved in various cellular processes requiring alteration of RNA secondary structure, including translation initiation, nuclear and mitochondrial splicing, and assembly of ribosomes and spliceosomes.
Some members of this family are associated with embryogenesis, spermatogenesis, and cellular growth and division.
The DDX4 gene encodes a DEAD box protein homologous to VASA proteins found in Drosophila and other species. It is specifically expressed in germ cell lineages of both sexes and plays a key role in germ cell development. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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