Thermo Fisher Scientific Epo Monoclonal Antibody (148436)
마우스 Erythropoietin(EPO)에 특이적인 Rat IgG2a 단일클론 항체. ELISA 및 중화(Neutralization) 분석에 적합. 단백질 A/G로 정제된 동결건조 형태로 제공되며, 보존제 무첨가. 연구용으로만 사용 가능.
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Applications
ELISA (ELISA)
- Tested Dilution: 0.5–2 µg/mL (Detection), 2–8 µg/mL (Capture)
Neutralization (Neu)
- Tested Dilution: 0.15–0.75 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 148436 |
| Immunogen | CHO-derived recombinant mouse Erythropoietin (Ala27–Arg192) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609655 |
Product Specific Information
- Reconstitute at 0.5 mg/mL in sterile PBS.
- Endotoxin level: <0.10 EU per 1 µg of antibody (LAL method).
Target Information
Erythropoietin (EPO) is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors. It induces final maturation of erythroid cells and production of red cell-specific proteins such as hemoglobin. The EPO receptor (EPOR) is highly expressed on precursor cells and decreases as cells mature.
In fetuses, hepatocytes are the main EPO source, while in adults, interstitial kidney cells dominate. EPO expression increases under hypoxia, and low levels are also found in lung and brain tissues. Recent studies suggest EPO may contribute to neuronal protection and tissue repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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