Thermo Fisher Scientific SMYD5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SMYD5. Recombinant protein control fragment (Product #RP-91632). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SMYD5,uniProtId:Q6GMV2-1,ncbiNodeId:9606,antigenRange:216-314,antigenLength:418,antigenImageFileName:PA5-53314_SMYD5_Q6GMV2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53314_SMYD5_Q6GMV2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647667

Product Specific Information

Immunogen sequence: QLELLRRLFT EALYEEAVSQ WFTPDGFRSL FALVGTNGQG IGTSSLSQWV HACDTLELKP QDREQLDAFI DQLYKDIEAA TGEFLNCEGS GLFVLQSCC

Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 95%.

Target Information

Retinoic acid (RA) represents the oxidized form of vitamin A and, via interactions with retinoic acid receptors (RARs), plays a crucial role in development, cellular growth and differentiation. The gene encoding RAI15 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alström syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.