Thermo Fisher Scientific DAP3 Monoclonal Antibody (OTI6E11), TrueMAB
Human DAP3 단백질(aa 161–398)에 특이적인 Mouse IgG1 단클론 항체로 Western blot에 최적화됨. 1 mg/mL 농도의 액상 형태이며, PBS/BSA/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Thermo Fisher Scientific DAP3 Monoclonal Antibody (OTI6E11), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E11 |
| Immunogen | Human recombinant protein fragment (aa 161–398 of human DAP3) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and assist in mitochondrial protein synthesis. Mitoribosomes consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. The DAP3 gene encodes a 28S subunit protein involved in apoptotic pathways initiated by TNF-α, Fas ligand, and IFN-γ. It may bind ATP/GTP and interact with mitoribosomal protein S27. Splice variants differ in the 5′ UTR but encode the same protein. Pseudogenes exist on chromosomes 1q and 2q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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