Thermo Fisher Scientific Gemin5 Polyclonal Antibody
Human Gemin5 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot 및 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제되었으며, TBS buffer에 0.1% BSA 포함. 연구용으로 사용되며 4°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1360 and 1410 of human Gemin5 (nuclear organelle associated protein 5) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), essential components of the spliceosome involved in pre-mRNA splicing. Sm proteins (SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, and SNRPG) form a heptameric ring on the Sm site of snRNA to create core snRNPs. In the cytosol, Sm proteins are held in an inactive 6S pICln-Sm complex by CLNS1A. The SMN complex dissociates CLNS1A and transfers Sm proteins to form active SMN-Sm complexes for nuclear transport. GEMIN5 functions as the snRNA-binding protein of the SMN complex.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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