Thermo Fisher Scientific CD2 Polyclonal Antibody
Rabbit polyclonal antibody against human CD2 protein. Validated for Western blot applications. Detects endogenous CD2 levels. Supplied as a liquid in PBS with 50% glycerol. For research use only.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CD2 (Accession P06729), corresponding to amino acid residues T251–G301 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899608 |
Product Specific Information
Antibody detects endogenous levels of total CD2.
Target Information
CD2 (LFA-2) is a monomeric surface antigen (MW 45–58 kDa) expressed on human T-lymphocytes, present on more than 95% of thymocytes and some natural killer cells, but not on B lymphocytes. It mediates adhesion between T cells and antigen-presenting cells through interaction with CD58. CD2 expression increases upon T cell activation, enhancing cell-cell contact and adhesion. CD2 deficiency can reduce intestinal inflammation and influence infection control. Disorders associated with CD2 dysfunction include penis squamous cell carcinoma and immune deficiency due to thymus absence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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