Thermo Fisher Scientific CD19 Polyclonal Antibody
CD19 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 및 마우스 시료에 반응합니다. Western blot, IHC, ICC/IF 등 다양한 실험에 사용 가능하며, 고순도 Affinity chromatography로 정제되었습니다. PBS 및 50% glycerol buffer에 보관하며 -20°C에서 안정적으로 유지됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CD19 (Accession P15391), corresponding to amino acid residues R474–H524 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899606 |
Product Specific Information
Antibody detects endogenous levels of total CD19.
Target Information
CD19 is a member of the immunoglobulin superfamily and has two Ig-like domains. It is expressed on 100% of peripheral B cells and is also found on certain myeloid leukemia cells. CD19 acts as a signal-amplifying coreceptor for the B cell receptor (BCR), regulating normal and malignant B cell proliferation. Mutations in CD19 can cause hypogammaglobulinemia, while overexpression leads to B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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