Thermo Fisher Scientific CD1a Polyclonal Antibody
CD1a 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 인간 및 랫트 반응성. 고순도 Affinity chromatography 정제 및 안정적 PBS/glycerol 저장용액 제공.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CD1A (Accession P06126), corresponding to amino acid residues M1–S46 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899607 |
Product Specific Information
Antibody detects endogenous levels of total CD1a.
Target Information
CD1a is a non-polymorphic MHC Class I related cell surface glycoprotein expressed in association with beta-2 microglobulin. It is found in cortical thymocytes, Langerhans cells, interdigitating cells, certain T-cell leukemias, and various other tissues.
CD1a mediates the presentation of lipid and glycolipid antigens to T cells. The human genome contains five CD1 family genes (CD1a–e) organized on chromosome 1, differing in localization and lipid ligand specificity. CD1a localizes to the plasma membrane and early endocytic vesicles. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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