Thermo Fisher Scientific Collagen Type V Polyclonal Antibody, FITC

Thermo Fisher Scientific Collagen Type V Polyclonal Antibody, FITC

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Store vial at 4°C prior to restoration.
• Restore with 0.05 mL of deionized water (or equivalent).
• For extended storage, aliquot contents and freeze at −20°C or below.
• Avoid repeated freeze/thaw cycles.
• Centrifuge if not clear after standing at room temperature.
• Stable for several weeks at 4°C as undiluted liquid.
• Dilute only prior to immediate use.
• Expiration date: one year from date of restoration.

Typically negligible cross-reactivity against other types of collagens was detected by ELISA against purified standards.
This antibody reacts with most mammalian Type V collagens and shows negligible cross-reactivity with Type I, II, III, IV, and VI collagens.
Non-specific cross-reaction with other human serum or extracellular matrix proteins is negligible.

Target Information

Type I collagen is the fibrillar collagen found in most connective tissues and the only component of collagen found in cartilage.
Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis.
Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.
Two transcripts, resulting from alternate polyadenylation signals, have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지