Thermo Fisher Scientific Phospho-AMOT (Ser175) Recombinant Rabbit Monoclonal Antibody (18H4L17)
Phospho-AMOT (Ser175) 특이적 재조합 토끼 단클론 항체로 높은 특이성과 재현성을 제공. Human 및 다중 종 반응 예측. Protein A 정제, 0.5 mg/mL 농도, 액상 형태. 세포 면역형광(ICC/IF)에 적합, 연구용으로만 사용.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 18H4L17 |
| Immunogen | Peptide corresponding to human AMOT [pS175] [aa172-aa179] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2762384 |
Product Specific Information
This antibody is predicted to react with Monkey, Sheep, Rabbit, and Mouse.
Recombinant rabbit monoclonal antibodies are produced via in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened for optimal production.
Advantages of recombinant rabbit monoclonal antibodies include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to rabbit immune repertoire
Target Information
AMOT (Angiomotin) belongs to the motin family of angiostatin-binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs.
AMOT plays a central role in tight junction maintenance through complexes with ARHGAP17, regulating polarity protein uptake.
Predominantly expressed in endothelial cells of capillaries and placental vessels, AMOT mediates angiostatin’s inhibitory effects on tube formation and endothelial migration during angiogenesis.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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(이미지 파일명: 702980_AMOT_Q4VCS5-1_Rabbit.svg, 702980_AMOT_Q4VCS5-1_Rabbit_PDP.jpeg)
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