Thermo Fisher Scientific C17orf96 Recombinant Rabbit Monoclonal Antibody (5H7L8)
Thermo Fisher Scientific의 C17orf96 Recombinant Rabbit Monoclonal Antibody (5H7L8)은 인간 및 생쥐에 반응하며 WB, ICC/IF, ChIP 분석에 적합합니다. 고특이성, 높은 재현성, 동물 유래 성분 무첨가, 장기 보관 안정성이 특징입니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ChIP assay (ChIP) | 2.5 µg/10^6 cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5H7L8 |
| Immunogen | Peptides corresponding to human C17orf96 [aa130-aa148, aa360-aa379] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2809223 |
Product Specific Information
This antibody is predicted to react with Monkey, Pig, Cat, and Dog.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal production candidates.
Advantages of recombinant rabbit monoclonal antibodies:
- Excellent specificity and sensitivity
- Consistent lot-to-lot performance
- Animal origin-free formulation
- Broader immunoreactivity due to large rabbit immune repertoire
Target Information
Elongin BC and Polycomb repressive complex 2-associated protein (EPOP), also known as C17ORF96, is a scaffold protein that bridges the PRC2/EED-EZH2 complex and the elongin BC complex.
It fine-tunes transcriptional regulation of polycomb group (PcG) target genes in embryonic stem cells (ESCs).
C17ORF96 plays a key role in genomic regions with both active and repressive chromatin properties, maintaining low-level expression of PcG target genes.
It recruits the elongin BC complex to limit PRC2/EED-EZH2 complex activity and interacts with USP7 to promote H2B deubiquitination at promoter sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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