Thermo Fisher Scientific Human LYN A, GST Tag Recombinant Protein
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
PV6450 | - | Thermo Fisher Scientific PV6450 Human LYN A, GST Tag Recombinant Protein 1 mg pk | 재고문의 | pk | 11,268,000원 | - | 12,394,800원 | |
PV6449 | - | Thermo Fisher Scientific PV6449 Human LYN A, GST Tag Recombinant Protein 100 ug pk | 재고문의 | pk | 2,613,000원 | - | 2,874,300원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Kinase Assay (KA)
Assay-dependent
Product Specifications
Species
Human
Expression System
Baculovirus
Amino acid sequence
Full length
Tag
GST-tag
Molecular weight
81 kDa
Class
Recombinant
Type
Protein
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
See Label
Purification
purified
Storage buffer
50nM tris HCl, pH 7.5, with 25% glycerol, 0.25mM DTT, 0.1mM EGTA, 150mM NaCl, 0.1mM PMSF, 0.1mM EDTA
Contains
no preservative
Storage conditions
-80° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Dry ice
Product Specific Information
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
• Increase disease relevance by interrogating a purified and active full-length LYN A reagent
• Uncover novel compounds or hits specific to the full length form
• Advance your research using the full-length protein and validated assays
Assay Platforms:
LanthaScreen™ TR-FRET Kinase Activity Assay
LanthaScreen™ Eu Kinase Binding Assay
Z`-LYTE™ Kinase Activity Assay
Protein Form: Full Length
The gene accession number for LYN A is NP_002341.1.
Target Information
LYN (v-yes-1 Yamaguchi sarcoma viral related oncogene homolog) is a SRC family kinase expressed predominantly in hematopoietic, neural, liver, and adipose tissue. It is a protein-coding gene and is associated with diseases such as alexia and chorea-acanthocytosis. Activation of LYN has been shown to lead to imatinib resistance in CML patients. LYN B and the slightly shorter LYN A are the two isoforms of LYN. An important paralog of Lyn Isoform A is FRK. The full length LYN A protein enables researchers to study important mechanisms underlying disease. Diseases associated with LYN include Sarcoma and Myeloid Leukemia. Among its related pathways are Signaling by Erythropoietin and Regulation of actin dynamics for phagocytic cup formation. Gene Ontology (GO) annotations related to Lyn Isoform A include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of Lyn Isoform A is HCK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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