Thermo Fisher Scientific Human PIK3CD/PIK3R1 (p110 delta/p85 alpha), His Tag Recombinant Protein

Applications

• Kinase Assay (KA): Assay-dependent

Product Specifications

Product Specific Information

For maximum recovery, please spin prior to use.
Aliquots below 20 µL are not recommended.
Do not store kinase diluted.
If properly stored at -80°C, product is guaranteed for 6 months from date of purchase.

PIK3CD/PIK3R1 (p110δ/p85α) recombinant human protein is:

• Available in 3 convenient sizes
• Validated in Adapta™ and Kinase Binding assays
• Full-length protein suitable for advanced kinase research

Related Assay Platforms:

• LanthaScreen™ Kinase Binding Assay
• Adapta™ Kinase Activity Assay

Protein Form: Recombinant, Full Length
Gene Accession Numbers:

• PIK3CD (p110δ): NP_005017.3
• PIK3R1 (p85α): NP_852664.1

Target Information

Phosphatidylinositol 3-kinase (PI3K) consists of a catalytic subunit (p110δ) and a regulatory subunit (p85α), encoded by PIK3CD and PIK3R1 genes.
PI3K phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring and plays a role in oncogenic transformation. It is highly expressed in AML blast cells and contributes to PIP3-mediated neutrophil polarization and directional migration.
PI3K signaling is involved in immune responses related to rheumatoid arthritis and other inflammatory diseases.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.